Ahh, prior authorization. Those sweet, seductive words that insurance companies lull themselves to sleep at night with dollar signs jumping over a fence in a pasture.
“Prior authorization” means that a doctor can’t prescribe a particular medication (or type of medication) without — you guessed it! — prior authorization from the insurance company. This usually means paperwork, phone calls, and hassle. More hassle than most docs want to bother with unless they really believe the medication is necessary for the continued health and well being of their patient. Insurance companies know this, of course, and so place some of the most expensive medications on the list that requires “prior authorization” to keep their costs low.
Well, that’s the theory anyway. But does it actually work in real life?
That’s the question a bunch of researchers from Harvard University, Eli Lilly and the Centers for Disease Control and Prevention decided to get the answer to, in a new study published Tuesday in the journal Health Affairs.
They compared 4,600 patients prescribed various medications to treat schizophrenia or a related disorder enrolled in the Medicaid program in Maine and New Hampshire. New Hampshire has no prior authorization requirements for medications, while Maine instituted such a program for certain atypical antipsychotics (which lasted for only 8 months before it was discontinued). Their only outcome measure was discontinuation of a given medication for more than 30 days. They didn’t measure the actual effectiveness of the medication (e.g., whether medication X actually resulted in decreased symptoms or increased psychosocial functioning for the patient), nor things like increased hospitalizations due to a medication change or discontinuation.
Nor did they measure, which they note in the study’s limitations, whether the prescription of atypical antipsychotics resulted in an increase in other health concerns (such as diabetes, as other studies have shown). Such an increase would create additional unmeasured costs, for the patient’s care and treatment of this new health concern, and could completely reverse the study’s findings. But left unmeasured, we don’t yet know whether this was an actual issue for patients in this study who were prescribed more atypical antipsychotics.
Medication discontinuation, as the authors note, is an important measure. But presented in a vacuum (as health policy journals sometimes do), one cannot really put these findings into any sort of proper context. So prior authorization results in the intended effect — a decrease in the expensive medications — but also unintended effects — increase discontinuation of the less effective medications and virtually no greater cost savings.
The upshot from this study? Prior authorizations, at least for atypical antipsychotics prescribed to people with schizophrenia, don’t really help cut costs, and could actually hurt people with this disorder (because of increased discontinuation of the ineffective medications). Further research is required to see whether these results — decreasing the use of prior authorization, especially for certain psychiatric medications — actually mean better patient outcomes or not, which this research did not measure.
Reference:
Soumerai et al. (2008). Use Of Atypical Antipsychotic Drugs For Schizophrenia In Maine Medicaid Following A Policy Change. Health Affairs, 10.1377/hlthaff.27.3.w185.
1 comment
From the article: ” … Medication discontinuation, as the authors note, is an important measure. But presented in a vacuum (as health policy journals sometimes do), one cannot really put these findings into any sort of proper context. …”
Eli Lilly underwrote the “study.” How could we expect a white-paper report that addresses all sides of the issue? No input from insurance carriers or doctors?
For a study in cherry picking, check the results of Lilly’s “clinical trials” for Strattera that were submitted to the FDA during the fast-tracked application for approval. They were measured in weeks and ended just before the thresholds for the emergence of dangerous side effects that had erupted in much earlier trials.
That was during clinical trials of the drug as an anti-depressant, Tomoxatin. (It was also tested as a weight-loss drug and treatment for binge eating before it wound up as Strattera.)
They stopped studies before reaching the points when participants in the early trials had begun to show aggression, hostility, suicidal thoughts (European reports claim scores of suicides), never mind subsequent liver damage.
When that failed, they recycled the drug under a different name (Strattera) and marketed it as a “safe, effective, non-stimulant alternative” drug to treat ADD/HD.
Strattera later earned a black box warning after the drug had been an explosive sales success for three years and amid reports that Lilly had deliberately and knowingly withheld information from the FDA.
Will we ever be free of:
— the FDA’s acceptance of “trials” that have been funded and ¬ reported by the companies that are pushing to have a drug approved?
— Company-issued press releases touting benefits with not a sentence about the risks/side effects?
— “Research” reports like this one, incomplete, manipulated and put in the best, pro-company light?
— Non-disclosure of the quiet “funding” (aka huge cash infusions) of the universities, and so-called research service providers, who conduct the studies FOR the companies?
— The unreported salaries/stipends paid to the researchers?
— The practice of having the drug companies’ in-house writers filter and file edited results?
— The routine of not investigating that the signatures of the researchers asserting the veracity of results aren’t from ones who had virtually no part in of the study (some never having heard of it until it was sent for their imprimatur?
We deserve better.
Thank you for this article.
rr